![]() ![]() The model captures the development and loss of resistance to insecticides, the effects of bed-net use on malaria control in a setting where proper and consistent use is not guaranteed, as well as differentiated biting of human hosts by resistant and sensitive mosquitoes. We present a model to investigate the effects of insecticide-treated bed-net use and mosquito-resistance and adaptation to pyrethroids used to treat bed nets on malaria prevalence and control in malaria endemic regions. Although this approach has been fairly successful, the gains are threatened by mosquito-resistance to pyrethroids, physical and chemical degradation of ITNs that reduce their efficacy, inconsistent and improper use by humans, etc. The main control method in malaria endemic regions has been through the use of pyrethroid-treated bed nets. Most of these cases and deaths are among children under five. Kenya for example, records about 3.5 million new cases and 11 thousand deaths each year. Malaria prevalence in sub-Saharan Africa remains high. ![]()
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